Allergic bronchopulmonary aspergillosis in paediatric cystic fibrosis patients.

@article{Almeida2006AllergicBA,
  title={Allergic bronchopulmonary aspergillosis in paediatric cystic fibrosis patients.},
  author={Marina Barbosa de Almeida and Maria Helena C F Bussamra and Joaquim Carlos Rodrigues},
  journal={Paediatric respiratory reviews},
  year={2006},
  volume={7 1},
  pages={67-72}
}
Allergic bronchopulmonary aspergillosis (ABPA) is a severe complication in children, adolescents and adults with cystic fibrosis (CF), the prevalence of which ranges from 6-25%. The disease is the result of the colonisation of the respiratory tract by fungi of the genus Aspergillus, commonly Aspergillus fumigatus, and subsequent host sensitisation to fungal antigens, accompanied by a Th2 CD4 type response mediated by the production of specific IgE. The consequent inflammatory and obstructive… CONTINUE READING