Allergic and non-allergic drug hypersensitivity reactions in children.

@article{Buonomo2010AllergicAN,
  title={Allergic and non-allergic drug hypersensitivity reactions in children.},
  author={Alessandro Buonomo and Giorgia Altomonte and Tiziana de Pasquale and Carla Lombardo and Valentina Pecora and V Sabato and Amira Colagiovanni and Angela Rizzi and Arianna Aruanno and Lucilla Pascolini and Giampiero Patriarca and Eleonora Nucera and Domenico Schiavino},
  journal={International journal of immunopathology and pharmacology},
  year={2010},
  volume={23 3},
  pages={881-90}
}
Adverse drug reactions (ADR) are an important medical problem. The aim of this study is to investigate the clinical characteristics of children with ADR and to assess the tolerability of alternative drugs in children (under 16 yrs of age) with a history of ADR. We studied 278 children (132 males and 146 females). Patients were studied by recording personal history and performing in vivo skin testing, in vitro laboratory tests and challenge tests. Patients who had experienced mild adverse… CONTINUE READING