Allergenicity and antigenicity of wild-type and mutant, monomeric, and dimeric carrot major allergen Dau c 1: destruction of conformation, not oligomerization, is the roadmap to save allergen vaccines.
Published 2007 in The Journal of allergy and clinical immunology
Carrot allergy is caused by primary sensitization to birch pollen. Continuous carrot exposure results in additional Dau c 1-specific allergic responses. Thus, immunotherapy with birch pollen may not improve the food allergy.
Evaluation of mutation and oligomerization of the major carrot allergen, Dau c 1, in regard to alteration of… CONTINUE READING