Allelochemical Activities of Pyrrolizidine Alkaloids: Interactions with Neuroreceptors and Acetylcholine Related Enzymes

@article{Schmeller1997AllelochemicalAO,
  title={Allelochemical Activities of Pyrrolizidine Alkaloids: Interactions with Neuroreceptors and Acetylcholine Related Enzymes},
  author={Thorsten Schmeller and Amany Abd-El-Fattah El-Shazly and Michael Wink},
  journal={Journal of Chemical Ecology},
  year={1997},
  volume={23},
  pages={399-416}
}
Thirteen pyrrolizidine alkaloids (PAs) 3′-acetylheliosupine, echihumiline, echihumiline N-oxide, echimidine, heliosupine, heliosupine N-oxide, heliotrine, monocrotaline, pycnanthine, retronecine, riddeline, senecionine, and seneciphylline) were analyzed for their interactions with acetylcholine-related enzymes, such as acetylcholine esterase (AChE), butyrylcholinesterase (BChE), choline acetyl transferase (ChAT), and neuroreceptors, such as α1- and α2-adrenergic, nicotinergic (nACh… CONTINUE READING

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