Allelic variants in TLR10 gene may influence bilateral affectation and clinical course of Meniere’s disease

@article{Requena2013AllelicVI,
  title={Allelic variants in TLR10 gene may influence bilateral affectation and clinical course of Meniere’s disease},
  author={Teresa Requena and Irene G{\'a}zquez and Antonia Garc{\'i}a Moreno and Angel Batuecas and Ismael Aran and Andr{\'e}s Soto-Varela and Sof{\'i}a Santos-P{\'e}rez and Nicolas Perez and Herminio P{\'e}rez-Garrigues and Alicia L{\'o}pez-Nevot and Eduardo Fuente Martin and Ricardo Sanz and Paz P{\'e}rez and Gabriel Trinidad and Marta E. Alarc{\'o}n-Riquelme and Roberto Teggi and Laura Zagato and Miguel {\'A}ngel L{\'o}pez-Nevot and Jose Antonio Lopez-Escamez},
  journal={Immunogenetics},
  year={2013},
  volume={65},
  pages={345-355}
}
Toll-like receptors trigger the innate immune response by activating various cell types such us macrophages and lymphocytes. We genotyped SNV of TLR3, TRL7, TLR8 and TLR10 in 863 Spanish and 150 Italian patients with Meniere’s disease (MD) and 1,013 controls by using Taqman assays. Real-Time qPCR was used to measure the expression level of TLR10 in… CONTINUE READING