Allelic polymorphisms and RFLP in the human immunoglobulin lambda light chain locus

@article{Lefranc1999AllelicPA,
  title={Allelic polymorphisms and RFLP in the human immunoglobulin lambda light chain locus},
  author={Marie-Paule Lefranc and Nathalie Pallar{\`e}s and Jean-Pol Frippiat},
  journal={Human Genetics},
  year={1999},
  volume={104},
  pages={361-369}
}
The organization of the human immunoglobulin lambda light chain locus (IGL) was recently described. This locus has been entirely sequenced. To evaluate the extent of the genomic variability existing inside that locus, we compiled all the available sequences of germline IGLV genes to find variants of Vλ sequences. We also looked for RFLP polymorphisms in a… CONTINUE READING