Allelic loss correlated with tissue specificity in head and neck squamous cell carcinomas and the clinical features of patients.

Head and neck squamous cell carcinomas (HNSCC) manifest various clinical behaviors according to their origin, i.e., from various parts of the head and neck mucosa. However, genetic factors involved in the carcinogenesis of HNSCC in different tissues have not yet been studied and evaluated. Three hundred and two specimens of HNSCC were characterized for… CONTINUE READING