Allelic frequencies of 3' Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia.

@article{Frezza2009AllelicFO,
  title={Allelic frequencies of 3' Ig heavy chain locus enhancer HS1,2-A associated with Ig levels in patients with schizophrenia.},
  author={Domenico Frezza and Vincenzo Giambra and Chiara Mattioli and K Piccoli and Raya Massoud and Alessandra Siracusano and Massimo di Giannantonio and Barbara K. Birshtein and Ivo Alex Rubino},
  journal={International journal of immunopathology and pharmacology},
  year={2009},
  volume={22 1},
  pages={115-23}
}
Infectious and autoimmune pathogenic hypotheses of schizophrenia have been proposed, prompting searches for antibodies against viruses or brain structures, and for altered levels of immunoglobulins. Previous experiments have shown that allele frequencies of the Ig heavy chain 3' enhancer HS1,2*A are associated with several autoimmune diseases, suggesting a possible correlation between HS1,2 alleles and Ig production. To test this, we analyzed levels of serum Igs and HS1,2*A genotypes in two… CONTINUE READING
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