Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance.

@article{Lin1998AllelicDA,
  title={Allelic deletion analyses of MMAC/PTEN and DMBT1 loci in gliomas: relationship to prognostic significance.},
  author={Heather Y Lin and Melissa L Bondy and Lauren A. Langford and Kenneth R. Hess and George L. Delclos and X ianchao Wu and W Chan and Mark A. Pershouse and W. K. Alfred Yung and Peter A. Steck},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1998},
  volume={4 10},
  pages={2447-54}
}
The frequency of loss of heterozygosity (LOH) around MMAC/PTEN and DMBT1 loci and survival analyses based on the LOH status were assessed in 110 patients with different histological groups of gliomas. Twenty-six of the patients had anaplastic oligodendrogliomas, 31 had anaplastic astrocytomas, and 53 had glioblastomas multiforme (GM). At the DMBT1 locus… CONTINUE READING