Allelic Losses at Chromosomes 1 p , 2 p , 6 p , 10 p , 13 q , 17 p , and 21 q Significantly Correlate with the Chromophobe Subtype of Renal Cell Carcinoma 1


We analyzed SO sporadic renal cell carcinomas (RCCs) for loss of heterozygosity (LOH) at the chromosomal regions 1p, 2p, 6p, 7q, 10p, lip, 13q, 14q, 17p, 21q, and 22q. Histologically, the tumors were distinguished into clear cell, chromophilic, and chromophobe carcinomas. Whereas LOH at 14q was identified in 42-64% of all three tumor types, only the… (More)

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