Allelic Diversity in Human Developmental Neurogenetics: Insights into Biology and Disease

  title={Allelic Diversity in Human Developmental Neurogenetics: Insights into Biology and Disease},
  author={Christopher A. Walsh and Elizabeth C. Engle},
One of the biggest challenges in neuroscience is illuminating the architecture of developmental brain disorders, which include structural malformations of the brain and nerves, intellectual disability, epilepsy, and some psychiatric conditions like autism and potentially schizophrenia. Ongoing gene identification reveals a great diversity of genetic causes underlying abnormal brain development, illuminating new biochemical pathways often not suspected based on genetic studies in other organisms… CONTINUE READING
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