Allele-specific associations of 5-HTTLPR/rs25531 with ADHD and autism spectrum disorder.

  title={Allele-specific associations of 5-HTTLPR/rs25531 with ADHD and autism spectrum disorder.},
  author={Kenneth D. Gadow and Carla J Devincent and Victoria I Siegal and Doreen M. Olvet and Saniya Kibria and Sarah F Kirsch and Eli Hatchwell},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
BACKGROUND The aims of the present study were to examine the association between a common serotonin transporter gene (SLC6A4) polymorphism 5-HTTLPR/rs25531 with severity of attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) symptoms. METHODS Mothers and teachers completed a validated DSM-IV-referenced rating scale for ADHD and ASD symptoms in 118 children with ASD. RESULTS Analyses indicated that children with at least one copy of the S or L(G) allele… CONTINUE READING
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