Allele specific PCR for the minor Histocompatibility antigen HA-2.

@article{Wilke2002AlleleSP,
  title={Allele specific PCR for the minor Histocompatibility antigen HA-2.},
  author={Martina Wilke and Jos Pool and Els Goulmy},
  journal={Tissue antigens},
  year={2002},
  volume={59 4},
  pages={304-7}
}
The hematopoietic system restricted minor Histocompatibility antigen (mHag), HA-2, is encoded by the novel human class I Myosin gene, MYO1G, located on the short arm of chromosome 7. The HA-2 encoding region is di-allelic and comprises the HLA-A2 restricted T cell epitope YIGEVLVSV (HA-2V) and its allelic counterpart YIGEVLVSM (HA-2M). We designed a sequence specific PCR (SSP) for both HA-2 alleles. The HA-2 genomic typing results were compared with the HA-2 CTL phenotyping in three families… CONTINUE READING