Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis.

@article{Teare2013AlleledoseAO,
  title={Allele-dose association of the C5orf30 rs26232 variant with joint damage in rheumatoid arthritis.},
  author={M Dawn Teare and Rachel Knevel and Michael L. Morgan and Agnieszka Kleszcz and P T J Emery and David J Moore and Philip J. Conaghan and Tom W. J. Huizinga and Ann W Morgan and Annette H. M. van der Helm-van Mil and Anthony Gerard Wilson},
  journal={Arthritis and rheumatism},
  year={2013},
  volume={65 10},
  pages={2555-61}
}
OBJECTIVE There is increasing evidence to indicate that genetic factors contribute significantly to radiologic joint damage in rheumatoid arthritis (RA). The aim of the present study was to determine whether genotypes of 10 recently identified RA susceptibility loci are associated with radiologic severity. METHODS A 2-stage study was performed using 3 Northern European RA populations: a British cross-sectional population (discovery cohort; n=885) and the Leiden Early Arthritis Clinic (EAC… CONTINUE READING