Allele-Specific DNA Methylation Detection by Pyrosequencing®.

Abstract

DNA methylation is an epigenetic modification that plays important roles in healthy as well as diseased cells, by influencing the transcription of genes. In spite the fact that human somatic cells are diploid, most of the currently available methods for the study of DNA methylation do not provide information on the methylation status of individual alleles… (More)
DOI: 10.1007/978-1-4939-2715-9_20

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