All-trans retinoic acid reduced skin involvement of adult T-cell leukemia

@article{Maeda2004AlltransRA,
  title={All-trans retinoic acid reduced skin involvement of adult T-cell leukemia},
  author={Yasuhiro Maeda and Takashi Yamaguchi and Satomi Ueda and Hajime Miyazato and Mitsuhiro Matsuda and Akihisa Kanamaru},
  journal={Leukemia},
  year={2004},
  volume={18},
  pages={1159-1160}
}
Adult T-cell leukemia (ATL) is a leukemia of mature peripheral T lymphocytes associated with human T-lymphotropic virus type I (HTLV-I). We previously reported that all-trans retinoic acid (ATRA) inhibited cell growth and induced apoptosis in HTLV-I (þ ) T-cell lines as well as fresh ATL cells obtained from ATL patients. Tsukasaki et al reported an interesting case in which ATRA induced complete remission for a patient with double hematological malignancies, acute promyelocytic leukemia and ATL… CONTINUE READING
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