All-trans retinoic acid induces mucociliary differentiation in a human cholesteatoma epithelial cell culture.

Abstract

OBJECTIVES Retinoic acid (RA) can prevent keratin formation and induce mucous differentiation in epithelia. In this study, we attempted to induce keratinizing squamous epithelium from human cholesteatoma epithelial (HCE) cells using an air-liquid interface (ALI) technique. We also examined the effect of RA on the phenotype of keratinizing HCE cells… (More)

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@article{Choi2004AlltransRA, title={All-trans retinoic acid induces mucociliary differentiation in a human cholesteatoma epithelial cell culture.}, author={Jae Young Choi and Kyu-Nam Cho and Joo-Heon Yoon}, journal={Acta oto-laryngologica}, year={2004}, volume={124 1}, pages={30-5} }