All-trans retinoic acid attenuates the renal interstitial fibrosis lesion in rats but not by transforming growth factor-β1/Smad3 signaling pathway.

Abstract

All-trans retinoic acid (ATRA) is an important therapeutic agent for prevention of the renal diseases. Transforming growth factor-β1 (TGF-β1)/Smad3 signaling pathway is a key signaling pathway which takes part in the progression of renal interstitial fibrosis (RIF). This investigation was performed to study the effect of ATRA in RIF rats and its effect on… (More)
DOI: 10.3109/0886022X.2012.745120

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Cite this paper

@article{Li2013AlltransRA, title={All-trans retinoic acid attenuates the renal interstitial fibrosis lesion in rats but not by transforming growth factor-β1/Smad3 signaling pathway.}, author={Zheng-Yi Li and T. X. Zhou and Yuan-Han Qin and Li-na Su and Hui-Ling Xu and Feng-Ying Lei}, journal={Renal failure}, year={2013}, volume={35 2}, pages={262-7} }