All subtypes of the Pmp adhesin family are implicated in chlamydial virulence and show species-specific function

@inproceedings{Becker2014AllSO,
  title={All subtypes of the Pmp adhesin family are implicated in chlamydial virulence and show species-specific function},
  author={Elisabeth Becker and Johannes H. Hegemann},
  booktitle={MicrobiologyOpen},
  year={2014}
}
The bacterial pathogens Chlamydia trachomatis and C. pneumoniae are obligate intracellular parasites, cause a number of serious diseases, and can infect various cell types in humans. Chlamydial infections are probably initiated by binding of the bacterial outer membrane protein OmcB to host cell glycosaminoglycans (GAGs). Here, we show that all nine members of the polymorphic membrane protein (Pmp) family of C. trachomatis mediate adhesion to human epithelial and endothelial cells. Importantly… CONTINUE READING

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