All platelets are not equal: COAT platelets.

@article{Alberio2004AllPA,
  title={All platelets are not equal: COAT platelets.},
  author={Lorenzo Alberio and Kenneth John Clemetson},
  journal={Current hematology reports},
  year={2004},
  volume={3 5},
  pages={
          338-43
        }
}
Collagen- and thrombin-activated (COAT) platelets were first described in 2000 and have attracted considerable interest, changing the interpretation of the way in which platelets contribute to thrombin generation and how their procoagulant activity is organized. Platelets activated by two agonists coming from glycoprotein VI or Fc gamma-receptor IIA agonists on the one hand and thrombin on the other produce a population of approximately 50% highly procoagulant active platelets. This subgroup is… CONTINUE READING

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