All layers of medial entorhinal cortex receive presubicular and parasubicular inputs.

@article{Canto2012AllLO,
  title={All layers of medial entorhinal cortex receive presubicular and parasubicular inputs.},
  author={Cathrin B. Canto and Noriko Koganezawa and Prateep Sanker Beed and Edvard I. Moser and Menno P Witter},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2012},
  volume={32 49},
  pages={17620-31}
}
The medial entorhinal cortex (MEC), presubiculum (PrS), and parasubiculum (PaS) are interconnected components of the hippocampal-parahippocampal spatial-representation system. Principal cells in all layers of MEC show signs of directional tuning, overt in head direction cells present in all layers except for layer II, and covert in grid cells, which are the major spatially modulated cell type in layer II. Directional information likely originates in the head direction-vestibular system and PrS… CONTINUE READING

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