All's well that ends dead

@article{Zheng1999AllsWT,
  title={All's well that ends dead},
  author={Timothy S. Zheng and Richard A Flavell},
  journal={Nature},
  year={1999},
  volume={400},
  pages={410-411}
}
When under attack from pathogens, the body expands its population of lymphoid cells. Once the pathogen has been destroyed, the excess cells must be eliminated, and this is done by cell suicide (apoptosis). People with a disease called type II ALPS cannot efficiently destroy the extra lymphoid cells, and it turns out that this is because they have mutations in a protein at the heart of apoptosis, caspase-10. 

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