Alkylidene Dihydropyridines As Synthetic Intermediates: Model Studies toward the Synthesis of the Bis(piperidine) Alkaloid Xestoproxamine C.

Abstract

Results of model studies demonstrating a stereoselective synthetic route to tricyclic analogues of the bis(piperidine) alkaloid xestoproxamine C are presented. Dearomatization of a tricyclic pyridine derivative to afford an alkylidene dihydropyridine (anhydrobase) intermediate followed by catalytic heterogeneous hydrogenation was used to install the correct… (More)

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@article{Lansakara2016AlkylideneDA, title={Alkylidene Dihydropyridines As Synthetic Intermediates: Model Studies toward the Synthesis of the Bis(piperidine) Alkaloid Xestoproxamine C.}, author={Ashabha I Lansakara and S. V. Santhana Mariappan and F Christopher Pigge}, journal={The Journal of organic chemistry}, year={2016}, volume={81 21}, pages={10266-10278} }