Alkannin and shikonin: effect on free radical processes and on inflammation - a preliminary pharmacochemical investigation.

@article{Kourounakis2002AlkanninAS,
  title={Alkannin and shikonin: effect on free radical processes and on inflammation - a preliminary pharmacochemical investigation.},
  author={Angeliki P. Kourounakis and Andreana N. Assimopoulou and Vassilios P. Papageorgiou and Antonis Gavalas and Panos N. Kourounakis},
  journal={Archiv der Pharmazie},
  year={2002},
  volume={335 6},
  pages={262-6}
}
Alkannin and shikonin, two natural products from Alkanna tinctoria and Lithospermum erhythrorhizon (Boraginaceae), are used in folk medicine where they are claimed to possess, among other properties, wound healing and anti-inflammatory activity. We investigated, together with the structurally related naphthazarin, their in vitro antioxidant and hydroxyl radical scavenging activity as well as their in vivo antiinflammatory activity. I was found that all examined compounds significantly inhibited… CONTINUE READING