Alkaloids from Leucojum vernum and antiretroviral activity of Amaryllidaceae alkaloids.

@article{Szlvik2004AlkaloidsFL,
  title={Alkaloids from Leucojum vernum and antiretroviral activity of Amaryllidaceae alkaloids.},
  author={L{\'a}szl{\'o} Szl{\'a}vik and Agnes Gyuris and J{\'a}nos Min{\'a}rovits and P{\'e}ter Forg{\'o} and J{\'o}zsef Moln{\'a}r and Judit Hohmann},
  journal={Planta medica},
  year={2004},
  volume={70 9},
  pages={871-3}
}
Three alkaloids, lycorine, homolycorine and 2- O-acetyllycorine, were isolated from the bulbs of Leucojum vernum (Amaryllidaceae) and identified by means of NMR analysis. The alkaloids obtained from L. vernum and from other Amaryllidaceae species were studied in vitro for HIV-1 replication inhibitory activity on MT4 cells. The cytotoxicity of the compounds in uninfected cells was evaluated by using the MTT assay and the [ (3)H]thymidine incorporation test. The antiviral activities were… CONTINUE READING

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