Alkaloid tolerance in Manduca sexta and phylogenetically related sphingids (Lepidoptera: Sphingidae)

@article{Wink2002AlkaloidTI,
  title={Alkaloid tolerance in Manduca sexta and phylogenetically related sphingids (Lepidoptera: Sphingidae)},
  author={Michael Wink and Vera Theile},
  journal={CHEMOECOLOGY},
  year={2002},
  volume={12},
  pages={29-46}
}
SummaryNicotine tolerance is well known for Manduca sexta. It also occurs in several other sphingids of the subfamilies Macroglossinae and Sphinginae. Only members of the subfamily Smerinthinae appear to be more susceptible to nicotine intoxication. Phylogenetic trees have been reconstructed from mitochondrial 16S rDNA and nuclear DNA to map nicotine tolerance.¶The nicotine binding site of both α-subunits of nicotinic acetylcholine receptors (nAChR) have been amplified and sequenced. No… 

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References

SHOWING 1-10 OF 61 REFERENCES

Androconial Hairbrushes of the Syntomis (Amata) phegea (L.) Group (Lepidoptera, Ctenuchinae): A Synapomorphic Character Supported by Sequence Data of the Mitochondrial 16S rRNA Gene

Males of several palaearctic Syntomis/Amata species (Lepidoptera: Arctiidae) possess androconial hairbrushes in connection with the foreleg coxa. The cuticular structure of these potentially

Sequence Data of Mitochondrial 16S rDNA of Arctiidae and Nymphalidae: Evidence for a Convergent Evolution of Pyrrolizidine Alkoloid and Cardiac Glycoside Sequestration

TLDR
The mitochondrial 16S rRNA gene of several arctiids was amplified by PCR and sequenced directly to reconstruct phylogenetic relationships between and within Arctiidae, Ctenuchidae, and Nymphalidae.

Excretion of alkaloids by malpighian tubules of insects.

TLDR
Nicotine transport in Rhodnius was unaffected by organic anions, such as amaranth and benzyl penicillin, or by the organic anion transport inhibitor, probenecid, and fluid secretion in 5-HT-stimulated tubules was reduced by atropine and nicotine.

Sequence evolution in mitochondrial ribosomal and ND-1 genes in lepidoptera: implications for phylogenetic analyses.

TLDR
Inability of molecular data to recover a well-established phylogeny may be rectified by additional characters or taxa, but it is clear that homoplasy is sufficiently high to caution against the acceptance of relationships generated with this molecular region that are not extremely robust.

The Bombycoidea: phylogeny and higher classification (Lepidoptera: Glossata)

TLDR
This paper is chiefly aimed at reassessing the limits of four bombycoid families, namely the Eupterotidae, Saturniidae, Lemoni family, and Brahmaeidae, and another newly proposed clade groups together the Endromidae, Mirinidae and Saturni family.

Induction of cytochrome P-450 activities by nicotine in the tobacco hornworm,Manduca sexta

TLDR
Results support the idea that induction of midgut cytochrome P-450-related metabolism is an adaptation of fifth-instarManduca sexta to dietary nicotine.
...