Alkaloid tolerance in Manduca sexta and phylogenetically related sphingids (Lepidoptera: Sphingidae)

  title={Alkaloid tolerance in Manduca sexta and phylogenetically related sphingids (Lepidoptera: Sphingidae)},
  author={Michael Wink and Vera Theile},
SummaryNicotine tolerance is well known for Manduca sexta. It also occurs in several other sphingids of the subfamilies Macroglossinae and Sphinginae. Only members of the subfamily Smerinthinae appear to be more susceptible to nicotine intoxication. Phylogenetic trees have been reconstructed from mitochondrial 16S rDNA and nuclear DNA to map nicotine tolerance.¶The nicotine binding site of both α-subunits of nicotinic acetylcholine receptors (nAChR) have been amplified and sequenced. No… 

Differences in Nicotine Metabolism of Two Nicotiana attenuata Herbivores Render Them Differentially Susceptible to a Common Native Predator

Results are consistent with the hypothesis that generalist herbivores incur costs of detoxification, which include the ecological costs of greater predation risks, in addition to the previously demonstrated energetic, physiological and metabolic costs.

Chemical ecology traits in an adaptive radiation: TPA-sensitivity and detoxification in Hyles and Hippotion (Sphingidae, Lepidoptera) larvae

It is postulate that proto-Hyles was polyphagous with the ability to use Euphorbia as food plants, and the species in South America, the origin of Hyles, can detoxify TPA, indicating this ability to be a plesiomorphic character state within the genus that enabled its adaptive radiation in the Palearctic, the distribution and diversity centre of Euphorba.

Sequestration of phorbol esters by aposematic larvae of Hyles euphorbiae (Lepidoptera: Sphingidae)?

Although H. euphorbiae caterpillars do not actively sequester phorbol esters, their aposematic colouration appears to be based on chemical defence through phorbl esters retained in the gut, even if some metabolism has taken place.

Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta.

Larval Helicoverpa zea Transcriptional, Growth and Behavioral Responses to Nicotine and Nicotiana tabacum

It is suggested that an observed coincidental rise in cannibalistic behavior and regulation of proteases and protease inhibitors in H. zea larvae signify a compensatory response to induced plant defenses.

Context-dependent medicinal effects of anabasine and infection-dependent toxicity in bumble bees

Variation in the effect of anabasine on infection suggests potential modulation of tritrophic interactions by both host genotype and environmental variables, and suggests that the medicinal effects and toxicity of an abasine may be context dependent.

Origin and Diversity of Metabolically Active Gut Bacteria from Laboratory-Bred Larvae of Manduca sexta (Sphingidae, Lepidoptera, Insecta)

It is concluded that the larval gut of Manduca sexta supported only a low diversity of metabolically active bacteria.

The metabolic fate of nectar nicotine in worker honey bees.




Androconial Hairbrushes of the Syntomis (Amata) phegea (L.) Group (Lepidoptera, Ctenuchinae): A Synapomorphic Character Supported by Sequence Data of the Mitochondrial 16S rRNA Gene

Males of several palaearctic Syntomis/Amata species (Lepidoptera: Arctiidae) possess androconial hairbrushes in connection with the foreleg coxa. The cuticular structure of these potentially

Sequence Data of Mitochondrial 16S rDNA of Arctiidae and Nymphalidae: Evidence for a Convergent Evolution of Pyrrolizidine Alkoloid and Cardiac Glycoside Sequestration

The mitochondrial 16S rRNA gene of several arctiids was amplified by PCR and sequenced directly to reconstruct phylogenetic relationships between and within Arctiidae, Ctenuchidae, and Nymphalidae.

Excretion of alkaloids by malpighian tubules of insects.

Nicotine transport in Rhodnius was unaffected by organic anions, such as amaranth and benzyl penicillin, or by the organic anion transport inhibitor, probenecid, and fluid secretion in 5-HT-stimulated tubules was reduced by atropine and nicotine.

Sequence evolution in mitochondrial ribosomal and ND-1 genes in lepidoptera: implications for phylogenetic analyses.

Inability of molecular data to recover a well-established phylogeny may be rectified by additional characters or taxa, but it is clear that homoplasy is sufficiently high to caution against the acceptance of relationships generated with this molecular region that are not extremely robust.

The Bombycoidea: phylogeny and higher classification (Lepidoptera: Glossata)

This paper is chiefly aimed at reassessing the limits of four bombycoid families, namely the Eupterotidae, Saturniidae, Lemoni family, and Brahmaeidae, and another newly proposed clade groups together the Endromidae, Mirinidae and Saturni family.

Induction of cytochrome P-450 activities by nicotine in the tobacco hornworm,Manduca sexta

Results support the idea that induction of midgut cytochrome P-450-related metabolism is an adaptation of fifth-instarManduca sexta to dietary nicotine.