Alkalinization by chloride/bicarbonate pathway in larval mosquito midgut.

  title={Alkalinization by chloride/bicarbonate pathway in larval mosquito midgut.},
  author={Dmitri Y. Boudko and Leonid L. Moroz and William R. Harvey and Paul Linser},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={98 26},
The midgut of mosquito larvae maintains a specific lumen alkalinization profile with large longitudinal gradients (pH approximately 3 units*mm(-1)) in which an extremely alkaline (pH approximately 11) anterior midgut lies between near-neutral posterior midgut and gastric cecum (pH 7-8). A plasma membrane H(+) V-ATPase energizes this alkalinization but the ion carriers involved are unknown. Capillary zone electrophoresis of body samples with outlet conductivity detection showed a specific… CONTINUE READING


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