Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial

@inproceedings{Pickkers2012AlkalinePF,
  title={Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial},
  author={Peter Pickkers and Suzanne Heemskerk and Jeroen A. Schouten and Pierre F. Laterre and Jean-Louis Vincent and Albertus B Beishuizen and Philippe Jorens and Herbert D. Spapen and Michael Bulitta and Wilbert H. M. Peters and Johannes Gerardus van der Hoeven},
  booktitle={Critical care},
  year={2012}
}
INTRODUCTION To evaluate whether alkaline phosphatase (AP) treatment improves renal function in sepsis-induced acute kidney injury (AKI), a prospective, double-blind, randomized, placebo-controlled study in critically ill patients with severe sepsis or septic shock with evidence of AKI was performed. METHODS Thirty-six adult patients with severe sepsis or septic shock according to Systemic Inflammatory Response Syndrome criteria and renal injury defined according to the AKI Network criteria… CONTINUE READING
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Medical Dictionary for Regulatory Activities , Maintenance and Support Services Organization

  • MedDRA MSSO
  • 2012

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