Alk8 is required for neural crest cell formation and development of pharyngeal arch cartilages

@article{PayneFerreira2003Alk8IR,
  title={Alk8 is required for neural crest cell formation and development of pharyngeal arch cartilages},
  author={T. Payne-Ferreira and P. Yelick},
  journal={Developmental Dynamics},
  year={2003},
  volume={228}
}
  • T. Payne-Ferreira, P. Yelick
  • Published 2003
  • Medicine, Biology
  • Developmental Dynamics
  • The type I TGFβ family member receptor alk8 acts in bone morphogenetic protein (BMP) signaling pathways to establish dorsoventral patterning in the early zebrafish embryo. Here, we present evidence that alk8 is required for neural crest cell (NCC) formation and that alk8 signaling gradients direct the proper patterning of premigratory NCCs. We extend our previous functional studies of alk8 to demonstrate that ectopic expression of constitutively active and dominant negative Alk8, consistently… CONTINUE READING
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    References

    SHOWING 1-10 OF 97 REFERENCES
    BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest.
    • 167
    • PDF
    Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation.
    • 150
    • Highly Influential
    • PDF
    Regulation of Tooth Development by the Novel Type I TGFβ Family Member Receptor Alk8
    • 23
    Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway.
    • 217
    • PDF
    sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.
    • 240
    • PDF
    Bmp activity establishes a gradient of positional information throughout the entire neural plate.
    • 263
    • PDF
    Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo.
    • 451
    • PDF