Alignment of Biological Macromolecules in Novel Nonionic Liquid Crystalline Media for NMR Experiments

@inproceedings{RuAlignmentOB,
  title={Alignment of Biological Macromolecules in Novel Nonionic Liquid Crystalline Media for NMR Experiments},
  author={M. Dolores Ru and Gottfried Otting}
}
n-Alkyl-poly(ethylene glycol)/ n-alkyl alcohol and glucopone/ n-hexanol mixtures are shown to form dilute liquid crystalline phases in aqueous solution which are suitable for partial alignment of biological macromolecules in a magnetic field. The constituent compounds are commercially available and inexpensive. The poly(ethylene glycol)-based systems are uncharged and thus insensitive with respect to pH, little sensitive with respect to salt, and tolerant against high protein concentrations… CONTINUE READING
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