Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform.

@article{Chew2007AlignedPC,
  title={Aligned Protein-Polymer Composite Fibers Enhance Nerve Regeneration: A Potential Tissue-Engineering Platform.},
  author={Sing Yian Chew and Ruifa Mi and Ahmet Hoke and Kam W Leong},
  journal={Advanced functional materials},
  year={2007},
  volume={17 8},
  pages={1288-1296}
}
Sustained release of proteins from aligned polymeric fibers holds great potential in tissue-engineering applications. These protein-polymer composite fibers possess high surface-area-to-volume ratios for cell attachment, and can provide biochemical and topographic cues to enhance tissue regeneration. Aligned biodegradable polymeric fibers that encapsulate human glial cell-derived neurotrophic factor (GDNF, 0.13 wt%) were fabricated via electrospinning a copolymer of caprolactone and ethyl… CONTINUE READING

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