Alignathon: a competitive assessment of whole-genome alignment methods.

@article{Earl2014AlignathonAC,
  title={Alignathon: a competitive assessment of whole-genome alignment methods.},
  author={Dent Earl and Ngan Nguyen and Glenn Hickey and Robert S. Harris and Stephen Fitzgerald and Kathryn Beal and Igor A. Seledtsov and Vladimir Molodtsov and Brian J. Raney and Hiram Clawson and Jaebum Kim and Carsten Kemena and Jia-Ming Chang and Ionas Erb and Alexander Poliakov and Minmei Hou and Javier M. Herrero and W. James Kent and Victor V. Solovyev and Aaron E. Darling and Jian Ma and Cedric Notredame and Michael Brudno and Inna Dubchak and David Haussler and Benedict Paten},
  journal={Genome research},
  year={2014},
  volume={24 12},
  pages={2077-89}
}
Multiple sequence alignments (MSAs) are a prerequisite for a wide variety of evolutionary analyses. Published assessments and benchmark data sets for protein and, to a lesser extent, global nucleotide MSAs are available, but less effort has been made to establish benchmarks in the more general problem of whole-genome alignment (WGA). Using the same model as the successful Assemblathon competitions, we organized a competitive evaluation in which teams submitted their alignments and then… CONTINUE READING
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