AlignMCL: Comparative analysis of protein interaction networks through Markov clustering

  title={AlignMCL: Comparative analysis of protein interaction networks through Markov clustering},
  author={Marco Mina and Pietro Hiram Guzzi},
  journal={2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops},
Evolutionary analysis and comparison of biological networks may result in the identification of conserved mechanism between species as well as conserved modules, such as protein complexes and pathways. Following an holistic philosophy several algorithms, known as network alignment algorithms, have been proposed recently as counterpart of sequence and structure alignment algorithms, to unravel relations between different species at the interactome level. In this work we present AlignMCL, a local… CONTINUE READING
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