Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in Populations

@article{Song2006AlgorithmsTD,
  title={Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in Populations},
  author={Yun S. Song and Zhihong Ding and Dan Gusfield and Charles H. Langley and Yufeng Wu},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  year={2006},
  volume={14 10},
  pages={1273-86}
}
Meiotic recombination is a fundamental biological event and one of the principal evolutionary forces responsible for shaping genetic variation within species. In addition to its fundamental role, recombination is central to several critical applied problems. The most important example is "association mapping" in populations, which is widely hoped to help find genes that influence genetic diseases (Carlson et al., 2004; Clark, 2003). Hence, a great deal of recent attention has focused on… CONTINUE READING