Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart.

@article{Lee2013AlgisylLVRWC,
  title={Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart.},
  author={Lik Chuan Lee and Samuel T Wall and Doron Klepach and Liang Ge and Zhihong Zhang and Randall J. Lee and Andy Hinson and Joseph H. Gorman and Robert C. Gorman and Julius M. Guccione},
  journal={International journal of cardiology},
  year={2013},
  volume={168 3},
  pages={2022-8}
}
BACKGROUND Left ventricular (LV) wall stress reduction is a cornerstone in treating heart failure. Large animal models and computer simulations indicate that adding non-contractile material to the damaged LV wall can potentially reduce myofiber stress. We sought to quantify the effects of a novel implantable hydrogel (Algisyl-LVR™) treatment in combination with coronary artery bypass grafting (i.e. Algisyl-LVR™+CABG) on both LV function and wall stress in heart failure patients. METHODS AND… CONTINUE READING