Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.

@article{Stapper2004AlginatePA,
  title={Alginate production affects Pseudomonas aeruginosa biofilm development and architecture, but is not essential for biofilm formation.},
  author={Andres Plata Stapper and Giri Narasimhan and Dennis E. Ohman and Johnny Barakat and Morten Hentzer and Soeren Molin and Arsalan Kharazmi and Niels H\oiby and Kalai Mathee},
  journal={Journal of medical microbiology},
  year={2004},
  volume={53 Pt 7},
  pages={679-90}
}
Extracellular polymers can facilitate the non-specific attachment of bacteria to surfaces and hold together developing biofilms. This study was undertaken to qualitatively and quantitatively compare the architecture of biofilms produced by Pseudomonas aeruginosa strain PAO1 and its alginate-overproducing (mucA22) and alginate-defective (algD) variants in order to discern the role of alginate in biofilm formation. These strains, PAO1, Alg+ PAOmucA22 and Alg- PAOalgD, tagged with green… CONTINUE READING
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