Alginate polylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane.

@article{Kulseng1997AlginatePM,
  title={Alginate polylysine microcapsules as immune barrier: permeability of cytokines and immunoglobulins over the capsule membrane.},
  author={B{\aa}rd Erik Kulseng and Beate Thu and Terje Espevik and Gudmund Skj{\aa}k-Braek},
  journal={Cell transplantation},
  year={1997},
  volume={6 4},
  pages={387-94}
}
Transplantation of pancreatic islets in alginate polylysine microcapsules is a potential useful method for treating type I diabetes. In this study, the permeability for alginate-polylysine microcapsules to cytokines an immunoglobulines has been investigated by a newly developed method. Magnetic monodisperse polymer particles (Dynabeads) coated with antibodies against selected proteins were encapsulated in 0.7 mm alginate polylysine microcapsules. The capsule membrane permeability to IgG (150… CONTINUE READING

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