Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms.

@article{Wozniak2003AlginateIN,
  title={Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms.},
  author={Daniel J Wozniak and Timna J O Wyckoff and Melissa Starkey and Rebecca Keyser and Parastoo Azadi and George A O'Toole and Matthew R. Parsek},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2003},
  volume={100 13},
  pages={7907-12}
}
The bacterium Pseudomonas aeruginosa causes chronic respiratory infections in cystic fibrosis (CF) patients. Such infections are extremely difficult to control because the bacteria exhibit a biofilm-mode of growth, rendering P. aeruginosa resistant to antibiotics and phagocytic cells. During the course of infection, P. aeruginosa usually undergoes a phenotypic switch to a mucoid colony, which is characterized by the overproduction of the exopolysaccharide alginate. Alginate overproduction has… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
126 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 126 extracted citations

Similar Papers

Loading similar papers…