Alginate Hydrogel Microencapsulation Inhibits Devitrification and Enables Large-Volume Low-CPA Cell Vitrification.

@article{Huang2015AlginateHM,
  title={Alginate Hydrogel Microencapsulation Inhibits Devitrification and Enables Large-Volume Low-CPA Cell Vitrification.},
  author={Haishui Huang and Jung Kyu Choi and Wei Rao and Shuting Zhao and Pranay Agarwal and Gang Zhao and Xiaoming He},
  journal={Advanced functional materials},
  year={2015},
  volume={25 44},
  pages={
          6939-6850
        }
}
Cryopreservation of stem cells is important to meet their ever-increasing demand by the burgeoning cell-based medicine. The conventional slow freezing for stem cell cryopreservation suffers from inevitable cell injury associated with ice formation and the vitrification (i.e., no visible ice formation) approach is emerging as a new strategy for cell cryopreservation. A major challenge to cell vitrification is intracellular ice formation (IIF, a lethal event to cells) induced by devitrification… CONTINUE READING
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