Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs.

@article{Meepagala2005AlgicidalAA,
  title={Algicidal and antifungal compounds from the roots of Ruta graveolens and synthesis of their analogs.},
  author={Kumudini M Meepagala and Kevin K. Schrader and David Wedge and Stephen O Duke},
  journal={Phytochemistry},
  year={2005},
  volume={66 22},
  pages={
          2689-95
        }
}
Bioassay-guided fractionation of the ethyl acetate extract of Ruta graveolens roots yielded rutacridone epoxide with potent selective algicidal activity towards the 2-methyl-isoborneol (MIB)-producing blue-green alga Oscillatoria perornata, with relatively little effect on the green alga Selenastrum capricornutum. The diol-analog of rutacridone epoxide, gravacridondiol, which was also present in the same extract, had significantly less activity towards O. perornata. Rutacridone epoxide also… CONTINUE READING
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