Algal Lectins as Potential HIV Microbicide Candidates

  title={Algal Lectins as Potential HIV Microbicide Candidates},
  author={Dana Huskens and Dominique Schols},
  booktitle={Marine drugs},
The development and use of topical microbicides potentially offers an additional strategy to reduce the spread of the Human Immunodeficiency Virus (HIV). Carbohydrate-binding agents (CBAs) that show specificity for high mannose carbohydrates on the surface of the heavily glycosylated envelope of HIV are endowed with potent anti-HIV activity. In fact, a number of algal lectins such as cyanovirin-N, microvirin, microcystis viridis lectin, scytovirin, Oscillatoria agardhii agglutinin and… CONTINUE READING


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