Alfentanil-oxygen anaesthesia for coronary artery surgery.

  title={Alfentanil-oxygen anaesthesia for coronary artery surgery.},
  author={S. de Lange and Theodore H. Stanley and Michael Jennings Boscoe},
  journal={British journal of anaesthesia},
  volume={53 12},
The anaesthétic properties of alfentanil were evaluated in 15 patients undergoing coronary artery bypass grafting operations. Alfentanil was infused at a rate of 3.0mg min-1 until the patients (breathing pure oxygen) became unconscious. Additional alfentanil 2.5-5.0mg i.v. was given if systolic arterial pressure increased by 15% or more from control values. Alfentanil produced unconsciousness in 75 +/- 18s, but muscle rigidity occurred in 27% of patients. Cardiovascular dynamics were minimally… CONTINUE READING