Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells

@inproceedings{Matsuda2016AlertCS,
  title={Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells},
  author={Naoyuki Matsuda},
  booktitle={Journal of intensive care},
  year={2016}
}
Sepsis refers to systemic inflammatory response syndrome and organ failure resulting from infection. Inflammatory receptors (e.g., Toll-like receptors and nucleotide oligomerization domain) recognize bacterial components as inflammatory ligands. These are expressed not only in leukocytes but also in major organs and vascular endothelial cells. “Alert cell” is defined as the cell that expresses the inflammatory receptor and intracellular signaling system to produce inflammatory mediators such as… CONTINUE READING
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