Alendronate in combination with calcium and vitamin D prevents bone loss after orthotopic liver transplantation: a prospective single-center study.

@article{Millonig2005AlendronateIC,
  title={Alendronate in combination with calcium and vitamin D prevents bone loss after orthotopic liver transplantation: a prospective single-center study.},
  author={Gunda Millonig and Ivo W. Graziadei and Dagmar Eichler and K. -J Pfeiffer and Gerd Finkenstedt and Petra Muehllechner and Alfred Koenigsrainer and Raimund Margreiter and Wolfgang Vogel},
  journal={Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society},
  year={2005},
  volume={11 8},
  pages={960-6}
}
Bone loss is a common complication in patients before and after liver transplantation (LT). The aim of this study was to investigate the efficacy of prophylactic treatment with bisphosphonates after LT in preventing progressive bone loss in LT patients. We included 136 patients with end-stage liver diseases awaiting LT. Bone mineral density (BMD) (by dual X-ray absorptiometry) and markers of bone metabolism were determined before, and 4, 12, 24, 36, and 48 months after LT. All patients received… CONTINUE READING