Aldosterone secretion by the mid-gestation ovine fetus: role of the AT2 receptor.


This study shows a short-term (3 h) infusion of ACTH but not angiotensin II (Ang II) stimulates aldosterone production in the mid-gestation fetus. No synergistic effect between ACTH and Ang II was observed. The fetal response was significantly less than observed in the adult animal when infused in a similar manner. Interestingly, plasma aldosterone could be… (More)


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