Aldosterone- and cortisol-co-secreting adrenal tumors: the lost subtype of primary aldosteronism.

@article{Spth2011AldosteroneAC,
  title={Aldosterone- and cortisol-co-secreting adrenal tumors: the lost subtype of primary aldosteronism.},
  author={Martin Sp{\"a}th and Svetlana Korovkin and Christiane Antke and Martin Anlauf and Holger S. Willenberg},
  journal={European journal of endocrinology},
  year={2011},
  volume={164 4},
  pages={447-55}
}
Current guidelines suggest proving angiotensin-independent aldosterone secretion in patients with primary aldosteronism (PA). It is further recommended to demonstrate unilateral disease because of its consequence for therapy. A general screening for excess secretion of other hormones is not recommended. However, clinically relevant autonomous aldosterone production rarely originates in adrenal tumors, compromised of zona glomerulosa cells only. This article reviews published data on aldosterone… CONTINUE READING

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Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
The presence of an aldosterone- and cortisol - co - secreting adrenocortical tumor should be considered if a patient has i ) PA and an adenoma that is larger than 2.5 cm , ii ) cortisol that is non - suppressible with overnight low - dose dexamethasone , or iii ) grossly elevated serum levels of hybrid steroids , such as 18-OH - F.
The presence of an aldosterone- and cortisol - co - secreting adrenocortical tumor should be considered if a patient has i ) PA and an adenoma that is larger than 2.5 cm , ii ) cortisol that is non - suppressible with overnight low - dose dexamethasone , or iii ) grossly elevated serum levels of hybrid steroids , such as 18-OH - F.
The presence of an aldosterone- and cortisol - co - secreting adrenocortical tumor should be considered if a patient has i ) PA and an adenoma that is larger than 2.5 cm , ii ) cortisol that is non - suppressible with overnight low - dose dexamethasone , or iii ) grossly elevated serum levels of hybrid steroids , such as 18-OH - F.
The presence of an aldosterone- and cortisol - co - secreting adrenocortical tumor should be considered if a patient has i ) PA and an adenoma that is larger than 2.5 cm , ii ) cortisol that is non - suppressible with overnight low - dose dexamethasone , or iii ) grossly elevated serum levels of hybrid steroids , such as 18-OH - F.
Aldosterone- and cortisol - co - secreting adrenal tumors : the lost subtype of primary aldosteronism .
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