Aldosterone aggravates glucose intolerance induced by high fructose.

Abstract

We previously reported that aldosterone impaired vascular insulin signaling in vivo and in vitro. Fructose-enriched diet induces metabolic syndrome including hypertension, insulin resistance, hyperlipidemia and diabetes in animal. In the current study, we hypothesized that aldosterone aggravated fructose feeding-induced glucose intolerance in vivo. Rats… (More)
DOI: 10.1016/j.ejphar.2013.10.051

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