Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.

@article{RiveraPrez2013AldehydeD3,
  title={Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.},
  author={Crisalejandra Rivera-P{\'e}rez and Marcela Nouzov{\'a} and Mark E. Clifton and Elena Martin Garcia and Elizabeth Leblanc and Fernando Gabriel Noriega},
  journal={Insect biochemistry and molecular biology},
  year={2013},
  volume={43 8},
  pages={675-82}
}
The juvenile hormones (JHs) play a central role in insect reproduction, development and behavior. Interrupting JH biosynthesis has long been considered a promising strategy for the development of target-specific insecticides. Using a combination of RNAi, in vivo and in vitro studies we characterized the last unknown biosynthetic enzyme of the JH pathway, a fatty aldehyde dehydrogenase (AaALDH3) that oxidizes farnesal into farnesoic acid (FA) in the corpora allata (CA) of mosquitoes. The AaALDH3… CONTINUE READING
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