Alcohols and neurotransmitter gated ion channels: past, present and future

@article{Lovinger1997AlcoholsAN,
  title={Alcohols and neurotransmitter gated ion channels: past, present and future},
  author={David M. Lovinger},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={1997},
  volume={356},
  pages={267-282}
}
  • David M. Lovinger
  • Published 1997
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • The neurotransmitter-gated ion channels form a superfamily of neurotransmitter receptors specialized for recognizing transmitters and rapidly gating ion channels that are contained within the same holoprotein complex. A large body of research indicates that alcohols alter the function of this class of receptor at concentrations relevant to the intoxicating and anesthetic effects of the alcohols. In addition, studies have implicated several types of neurotransmitter-gated channels in… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 107 CITATIONS, ESTIMATED 49% COVERAGE

    Acute Alcohol Action and Desensitization of Ligand-Gated Ion Channels

    VIEW 12 EXCERPTS
    CITES BACKGROUND

    Dual action of n-alcohols on neuronal nicotinic acetylcholine receptors.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Alcohol and NMDA receptor: current research and future direction

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Synaptic targets: Chronic alcohol actions

    VIEW 9 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    1998
    2020

    CITATION STATISTICS

    • 6 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 116 REFERENCES

    Rings of anionic amino acids as structural determinants of ion selectivity in the acetylcholine receptor channel

    Recent developments in alcoholism:neuronal ion channels.

    • E. Sanna, Robert Alan Harris
    • Chemistry, Medicine
    • Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism
    • 1993

    Transmembrane topology of two kainate receptor subunits revealed by N-glycosylation.

    Alcohol action on a neuronal membrane receptor: evidence for a direct interaction with the receptor protein.

    Cloned glutamate receptors.

    A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain