Alcoholism and major depression in women. A twin study of the causes of comorbidity.

@article{Kendler1993AlcoholismAM,
  title={Alcoholism and major depression in women. A twin study of the causes of comorbidity.},
  author={Kenneth S. Kendler and A Christopher Heath and Michael C. Neale and Ronald C Kessler and Lindon J. Eaves},
  journal={Archives of general psychiatry},
  year={1993},
  volume={50 9},
  pages={690-8}
}
BACKGROUND Although major depression (MD) and alcoholism co-occur in clinical and epidemiologic samples of women more often than expected by chance, the magnitude and causes of this comorbidity are uncertain. METHODS Personal interviews were conducted with 2163 female twins from a population-based twin registry. Bivariate twin analysis was performed using two definitions of MD and three definitions of alcoholism of varying diagnostic breadth. RESULTS Odds ratios ranged from 2.7 to 6.0 and… CONTINUE READING